Interrelation between rheumatoid arthritis activity and pathogenetic variant of an anemia complicating its course
Kalinkina N.V. , Bachteeva T.D. , Smyrnova G.S. , Vatutin M.T.
Summary. The purpose of the study was to estimate interrelation between rheumatoid arthritis (RA) activity and pathogenetic variant of an anemia complicating its course. 57 patients with RA and anemia were examined. At 42 (73.7%) of them (1st group) iron deficiency anemia (IDA) was revealed, at 15 (26.3%) — anemia of chronic disease (ACD) (2nd group). All patients received a methotrexate in an average dose 11.25±3.75 mg/weekly in a combination with folic acid. Steroid hormones periodically received 41 (71.9%) patients in an average dose 19.6±8.2 mg/d. For the estimation of the RA course 66/68 joint count, Visual Analogue Scale and questionnaires were used, the radiological stage of disease and its activity were defined. Results of research have shown that patients with longer current and high RA activity have IDA, while patients with mild disease activity have ACD.
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