To the topic of concomitant administration of no-steroidal anti-inflammatory drugs and aspirin — pharmacological interaction, efficacy, approaches to individualized drug choice

Summary. The data from clinical and experimental studies devoted to the investigation of pharmacological interaction between main representatives of non-steroidal anti-inflammatory drugs (NSAIDs) and low dosage of aspirin are presented in the article. The approaches to the individualized choice of NSAID, taking into account the levels of gastrointestinal and cardio-vascular risks in patient with rhematic disease are described.