SIGNIFICANSE OF DYSLIPIDEMIA IN PATHOGENESIS OF OSTEOARTHRITIS WITH CONCOMITANT ESSENTIAL HYPERTENSION

Kolomiets V.V. ¹, Rogachova T.A.²

• ¹Донецкий государственный медицинский университет
• ²Донецкий национальный медицинский университет им. Максима Горького

Summary. Summary. Purpose. Study influence of dyslipidemia on manifestation of joint syndrome and diurnal blood pressure (BP) profile in patients with osteoarthritis (OA) and concomitant essential hypertension (EH). Subject and methods. Blood lipids, interleukin-1 content, tumor necrosis factor-α), С-reactive protein, Leken’s index, C-terminal telopeptide, calcium transport between skeleton and blood, endothelium function, diurnal BP profile were determined in 120 patients with OA and concomitant EH and in 60 patients with EH (comparison groop). Spinal radiographic densitometry was performed. Results. In patients with ОА in combination with EH in a greater degree (p3.80 mmol/l). Conclusion. Dyslipidemia is one of the common pathogenetic mechanisms of OA and EH.