CASE OF ABDOMINAL ISCHEMIC SYNDROME OF ATHEROSCLEROTIC ORIGIN IN PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS

Voloshyn O.I.¹, Kоpchak V.M.², Kоpchak K.V.², Voloshyna L.O.³, Honchar L.V.², Kondratyuk V.A.²

• ¹Bukovinian State Medical University, Chernivtsi
• ²Національний інститут хірургії та трансплантології ім. О.О. Шалімова НАМН України
• ³Буковинська державна медична академія, Чернівці

Summary. Summary. The article describes the clinical case of severe abdominal ischemic syndrome of atherosclerotic origin in 42-year-old patient with systemic lupus erythematosus (SLE). Differential diagnosis and confirmation of atherosclerotic lesion of thoracic and abdominal aorta and its branches has been reached by X-ray and magnetic resonance computer diagnostics, vascular contrast methods. It was proved that effectiveness of pathogenetically grounded aggressive combination of pulse therapy (1000 mg prednisone, cyclophosphamide 1000 mg) repeated courses in exacerbations (a total of more than 100-pulse infusion for 12 years) and subsequent maintenance therapy with prednisolone 120 to 50–30 mg on the basis of gastroprotektors, hypotensive drugs, potassium, calcium metabolism correctors, symptomatic drugs. Price of this therapy — transfer from subacute SLE with high activity and renal disease with nephrotic syndrome, heart, lungs, joints, skin and cerebrovascular lesions in chronic SLE with minimal activity of renal disease without nephrotic syndrome, skin and joints, lengthening of life expectancy at 32 years, but with the development of early and pronounced atherosclerotic vascular lesions predominantly abdominal, steroid-induced osteoporosis of bone apparatus, compression of L_І–L_ІІІ Kushingoid syndrome.