TISSUE HISTOPATHOLOGY OF THE HIP JOINT, OCCURRENCE FREQUENCY AND CORRELATIONS OF MORPHOLOGICAL INDICES AT SEVERE DYSPLASTIC COXARTHROSIS
Grigorovsky V.V. , Babko A.M., Huzhevskyi I.V., Poluliakh D.M.
Summary. Research objective was to determine frequency differences and correlations of some morphological indices of the femoral head condition in patients at severe dysplastic coxarthrosis (DCA). As research material served tissues of the hip joint from 17 patients (9 men and 8 women) with DCA, developed owing to congenital dysplasia of acetabulum, in which total joint arthroplasty was carried out. The condition of articular cartilage, subchondral and deep spongiosa, and synovial cover condition as fibrous layer were estimated. The statistical and correlation analysis were carried out. Results and conclusions. In a complex of femoral head articular surface changes the most essential are: deformation, due to the dystrophy of articular cartilage thickness reduction, superficial and deep cartilage destruction a, surface and marginal osteochondral exostoses, dystrofic-destructive changes of subchondral spongiosa tissues. In the articular capsule signs of chronic productive-infiltrative inflammation are defined. Between indices of femoral head tissues conditions by DCA there were found some correlations, the greatest parametres of association coefficient among which were: a) «stage of dysplastic coxarthrosis» — «marginal osteochondral exostoses» — correlation negative, week, significant (р<0,1); b) «stage of dysplastic coxarthrosis» — «dystrophic-dysplastic changes in femoral head spongiosa» — correlation positive, of moderate closeness, high significant (р<0,02); c) «marginal osteochondral exostoses» — «dystrophic-dysplastic changes in femoral head spongiosa» — correlation negative, of moderate closeness, significant (р<0,05).
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