The role of hyperuricemia in development of the cardiovascular diseases

Shuba N.M. , Voronova T.D., Litvinenko S.V.

• National Medical Academy of Postgraduate Education named after P.L. Shupik, Kyiv

Summary. Here is the last data of the hyperuricemia and xantionoxidase role in particular at the cardiovascular diseases, such as arterial hypertension, heart failure, myocardial infarction pathogenesis because of hyperuricemia incidences rising at the last years (epidemiological USA data, 2007–2008). Importance of hyperuricemia level effective control was shown in lowering the incidence of general and cardiovascular death, heart failure, atrial fibrillation and others chronic heart diseases. Importance of selective xantionxodase inhibition was proven especially when high level occurs, in renal insufficiency in particular and for endothelial disfunction prevention.