hyposalivation is a Clinical Marker and AGRAVATOR OF COURSE OF rheumatoid arthritis COMPLICATED BY lesion of the esophagus
Zazdravnov A.A. , Andrusha A.B.
Summary. Summary. The article describes the features of salivatory disorders in patients with rheumatoid arthritis (RA), their role in the pathogenesis of esophageal complications. 149 patients with RA, of whom 99 had esophageal complications were examined. In all cases, the pathology of the esophagus was diagnosed no earlier than 1 year after the diagnosis of RA. Statistical processing of the results of this investigation revealed a positive association between the presence of esophageal complications on the one hand and the xerostomia, the presence of incomplete dentition, manifestations glossitis/stomatitis — on the other. It was established relationship between the level of hyposalivation and the presence of lesions of the esophagus in patients with RA. The number of functionally active minor salivary glands in patients with RA decreased in the presence of esophageal complications compared with patients with RA, but without abnormalities of the esophagus. The rate of salivation and the number of functionally active minor salivary glands decreased with an increase in the activity of RA. The conclusion was that hyposalivation in patients with RA and esophageal complications reflects the activity of the pathological process and is an aggravating factor. Hyposalivation involved in the formation of extra-articular manifestations of RA.
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