Risk of development and peculiarities of nefropathy in patients with systemic sclerosis

Kuryata O.V.¹, Lysunets T.K.², Karavanska I.L. ¹, Semenov V.V.³

• ¹Державний заклад «Дніпропетровська медична академія МОЗ України»
• ²Комунальний заклад «Дніпропетровська обласна клінічна лікарня ім. І.І. Мечникова»
• ³ГУ «Днепропетровская медицинская академия МЗ Украины»

Summary. Summary. To risk of development and peculiarities of nefropathy in patients with systemic sclerosis (SSc) was investigated. A 5-year prospective study of 81 patients with SSc, who are in the regional registry, regularly surveyed and get regular medical care in a rheumatology department was carried out. It was found that patients with dcSSc had more severe fibrotic changes – pneumofibrosis and skin thickening, and in patients with lcSSc were more defined features of vascular pathology — arterial hypertension. The earliest and the most reliable marker of kidney damage is proteinuria. Prevalence of arterial hypertension correlates with severity of nephropathy.