Survival analysis of patients with pulmonary arterial hypertension associated with connective tissue disease
Sirenko Yu.M., Radchenko G.D. , Garmish O.O., Deiak S.I., Zhivilo I.O., Botsiuk Yu.A.
Summary. We presents an analysis of the survival of patients with pulmonary arterial hypertension associated with connective tissue disease for the period 2014–2021 on the basis of the Department of Secondary and Pulmonary Hypertension of the SI «National Scientific center «Institute of Cardiology named after acad.M.D.Strazheska» National academy of Medical Science of Ukraine. According to our center, the share of such patients was 6.1% (28 pts.). All patients underwent standard physical examination, standard and biochemical blood tests, 6-minute walk test, echocardiographic examination and right heart catheterization with thermodilution. Survival analysis using Kaplan-Meier curves found that patients with pulmonary arterial hypertension associated with connective tissue disease showed one of the worst rates — 51.2%. In this group of patients, 1-, 2- and 3-year survival was 93.3%, 86.8% and 81.5%, respectively. Our results were a few different from the results of other countries, which is the stimulus for the initiation of new early nationwide registry studies involving patients with pulmonary arterial hypertension in modern conditions in Ukraine.
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